The philosophy of biology is one of the most exciting new areas in the field of philosophy and one that is attracting much attention from working scientists. This Companion, edited by two of the founders of the field, includes newly commissioned essays by senior scholars and up-and-coming younger scholars who collectively examine the main areas of the subject - the nature of evolutionary theory, classification, teleology and function, ecology, and the problematic relationship between biology and religion, among other topics. Up-to-date (...) and comprehensive in its coverage, this unique volume will be of interest not only to professional philosophers but also to students in the humanities and researchers in the life sciences and related areas of inquiry. (shrink)

Drawing on work of the past decade, this volume brings together articles from the philosophy, history, and sociology of science, and many other branches of the biological sciences. The volume delves into the latest theoretical controversies as well as burning questions of contemporary social importance. The issues considered include the nature of evolutionary theory, biology and ethics, the challenge from religion, and the social implications of biology today (in particular the Human Genome Project).

Compares classic and contemporary theories of genetics and evolution and explores the role of teleological thought in biology.

“Hildebrand has constructed a well-paced and historically informative evaluation of neopragmatism. . . . This book makes an excellent companion for courses in both contemporary epistemology and American philosophy.” –Choice How faithful are the Neopragmatists' reformulations of Classical Pragmatism? Can their Neopragmatisms work? In examining the difficulties in Neopragmatism, David L. Hildebrand is able to propose some distinct directions for Pragmatism.

Extreme variation in the meaning of the term “species” throughout the history of biology has often frustrated attempts of historians, philosophers and biologists to communicate with one another about the transition in biological thinking from the static species concept to the modern notion of evolving species. The most important change which has underlain all the other fluctuations in the meaning of the word “species” is the change from it denoting such metaphysical entities as essences, Forms or Natures to denoting classes (...) of individual organisms. Several authors have taken notice of the role of metaphysics in the work of particular biologists. An attempt will be made in this paper to present a systematic investigation of the role which metaphysics has played in the work of representative biologists throughout the history of biology, especially as it relates to their species concepts. (shrink)

The dynamical hypothesis states that cognitive systems are dynamical systems. While dynamical systems play an important role in many cognitive phenomena, the dynamical hypothesis as stated applies to every system and so fails both to specify what makes cognitive systems distinct and to distinguish between proposals regarding the nature of cognitive systems. To avoid this problem, I distinguish several different types of dynamical systems, outlining four dimensions along which dynamical systems can vary: total-state versus partial-state, internal versus external, macroscopic versus (...) microscopic, and systemic versus componential, and illustrate these with examples. I conclude with two illustrations of partial-state, internal, microscopic, componential dynamicism. (shrink)

Theories in cognitive science, and especially cognitive neuroscience, often claim that parts of cognitive systems are reused for different cognitive functions. Philosophical analysis of this concept, however, is rare. Here, I first provide a set of criteria for an analysis of reuse, and then I analyse reuse in terms of the functions of subsystems. I also discuss how cognitive systems execute cognitive functions, the relation between learning and reuse, and how to differentiate reuse from related concepts like multi-use, redundancy, and (...) duplication of parts. Finally, I illustrate how my account captures the reuse of dynamical subsystems as unveiled by recent research in cognitive neurobiology. This recent research suggests two different evolutionary justifications for reuse claims. (shrink)

In this essay we discuss a class of apparently metaphorical idioms, exemplified by “fine as frog's hair,” that do not afford any obvious interpretation, and appear to have originated, at least in part, in language play. We review recent trends in both play theory and metaphor theory, and show that a playful approach to language is often an important element in the use and understanding of metaphors (and idioms generally), even when metaphors can be readily interpreted by means of a (...) vehicle-to-topic mapping. Based on this evidence we call for a more deliberate inclusion of language play in metaphor theory and analysis. (shrink)

Response to wrongdoing is modeled as a decision process in an organizational context. The model is grounded in theory of risk, ambiguity, and informational influences on decision making. Time pressure, inadequate information and coworker influences are addressed. Along the way, a handful of propositions are provided which emphasize influences on the actual choice between response options.

When there have been substantial failures by institutional leadership in their oversight responsibility to protect research integrity, the public should demand that these be recognized and addressed by the institution itself, or the funding bodies. This commentary discusses a case of research failures in developing genomic predictors for cancer risk assessment and treatment at a leading university. In its review of this case, the Office of Research Integrity, an agency within the US Department of Health and Human Services, focused their (...) report entirely on one individual faculty member and made no comment on the institution’s responsibility and its failure to provide adequate oversight and investigation. These actions missed an important opportunity to emphasize the institution’s critical responsibilities in oversight of research integrity and the importance of institutional transparency and accountability. (shrink)

Much has been written about prisoner research and the controversies surrounding prisoners as human subjects. The Institute of Medicine recently released a report addressing some of these issues. This report, which generated further controversy, needs to be fully discussed in the literature and certain aspects are examined in this work. Further, in the body of literature there has been little acknowledgement of the concept of the right of prisoners to be involved in research. This needs to be pursued from an (...) ethical perspective and eventually a legal one. This paper explores that concept and documents some facilities in which a prisoner's right to research has occurred. (shrink)

According to the somatic mutation theory (SMT), cancer begins with a genetic change in a single cell that passes it on to its progeny, thereby generating a clone of malignant cells. It is strongly supported by observations of leukemias that bear specific chromosome translocations, such as Burkitt's lymphoma, in which a translocation activates the c‐myc gene, and chronic myeloid leukemia (CML), in which the Philadelphia chromosome causes production of the BCR‐ABL oncoprotein. Although the SMT has been modified and extended to (...) encompass tumor suppressor genes, epigenetic inheritance, and tumor progression through accumulation of further mutations, perhaps the strongest validation comes from the successful treatment of certain malignancies with drugs that directly target the product of the mutant gene.magnified imageDavid Vaux is at the Walter and Eliza Hall Institute and La Trobe Institute for Molecular Science, Melbourne, Australia. (shrink)

In a recent paper, William K. Goosens objects to the arguments I set out some time ago attacking the logical empiricist analysis of reduction as applied to genetics. In these works I did not argue against the claim that Mendelian genetics was being reduced to molecular biology. Nor did I conclude, as Goosens asserts, that in the case of genetics, “reduction is insignificant”. To the contrary, I repeatedly stated that, “given our pre-analytic intuitions about reduction,” the reduction of Mendelian to (...) molecular genetics “is a case of reduction, a paradigm case”. And in agreement with Kenneth Schaffner I argued that reduction “in some very important, pre-analytic sense has taken place and is taking place in genetics”. The target of my objections to reduction in genetics was not “reduction” in some pre-analytic sense. Nor was it the various explications which have appeared since. Rather it was the notion of theory reduction set out a generation ago by such logical empiricists as Ernest Nagel, The particular version of this analysis which I chose to attack was that presented by Schaffner ; for Schaffner's later views, see his. I chose Schaffner's explication to attack because I thought it was the best of its kind and because it was the only defense of the logical empiricist analysis at the time which used genetics as one of its chief examples. Contrary to Goosens' assumption, in criticizing Schaffner's explication, I did not thereby “endorse” it. (shrink)

Several important terms in biology have recently been criticized for not being "operational." In this paper the course of operationism in physics, psychology and genetics is sketched to show what effect this particular view on the meaning of scientific terms had on these disciplines. Then the biological species concept and the concept of homology are examined to see in what respects they are or are not "operational." One of the primary conclusions of this investigation is that few terms in science (...) are completely operational or completely nonoperational. Some scientific terms, especially theoretical terms, are a good deal less operational than others; but, far from being regrettable, this situation is essential if theoretical terms are to fulfill their systematizing function and if scientific theories are to be capable of growth. (shrink)

Intentionality, as Brentano originally introduced the term in modern philosophy, was meant to provide a distinctive characteristic definitively separating the mental from the physical.(1) Mental states have an intrinsic relationship to an object, to that which they are "about." Physical entities just are what they are, they cannot, by their very essence, refer to anything, they have no "outreach", as one might put it. Mental states have, as it were, an incomplete essence, they cannot exist at all unless they are (...) completed by something other than themselves, their object. Brentano's position is opposed to all theories which represent the mental as only extrinsically related to the world, that is, to all theories in which mental states are themselves self-sufficient for their own existence and only secondarily relate to the world by means of something external to their nature, e.g., neurological causation, divine intervention, or pre-established harmony. In these later cases, any mental act whatsoever could be related to any object, or indeed to none, for the relation is external to the nature of the act, it is superimposed on it by outside forces. Brentano's point is that a mental act has, by its very essence, an Intentional object without which it would not be a mental act. It would therefore appear that since causality is an external relationship which could in principle relate any two things regardless of their nature, the Intentional relation between an act and its object cannot be a causal relation. (shrink)

As sociologists deepen their examinations of human rights in their teaching, research, and thinking, it is essential that such work is conducted in a manner that is both mindful and critical of the knowledge we are building upon in sociology and human rights. As the authors of this volume reveal, creating sociological knowledge that examines human rights for the expansion of human rights is something that sociologists are well equipped to undertake, whether through the use of mathematics, comparative-historical analysis, the (...) study of emotions, conversations, or social psychology. In these chapters you will find the roots of the study of human rights deep within sociological research and thinking as well as emerging techniques that will push the discipline as it seeks to expand understanding of human rights together with so many other aspects of the social condition. (shrink)

Authors frequently refer to gene-based selection in biological evolution, the reaction of the immune system to antigens, and operant learning as exemplifying selection processes in the same sense of this term. However, as obvious as this claim may seem on the surface, setting out an account of “selection” that is general enough to incorporate all three of these processes without becoming so general as to be vacuous is far from easy. In this target article, we set out such a general (...) account of selection to see how well it accommodates these very different sorts of selection. The three fundamental elements of this account are replication, variation, and environmental interaction. For selection to occur, these three processes must be related in a very specific way. In particular, replication must alternate with environmental interaction so that any changes that occur in replication are passed on differentially because of environmental interaction. One of the main differences among the three sorts of selection that we investigate concerns the role of organisms. In traditional biological evolution, organisms play a central role with respect to environmental interaction. Although environmental interaction can occur at other levels of the organizational hierarchy, organisms are the primary focus of environmental interaction. In the functioning of the immune system, organisms function as containers. The interactions that result in selection of antibodies during a lifetime are between entities (antibodies and antigens) contained within the organism. Resulting changes in the immune system of one organism are not passed on to later organisms. Nor are changes in operant behavior resulting from behavioral selection passed on to later organisms. But operant behavior is not contained in the organism because most of the interactions that lead to differential replication include parts of the world outside the organism. Changes in the organism's nervous system are the effects of those interactions. The role of genes also varies in these three systems. Biological evolution is gene-based (i.e., genes are the primary replicators). Genes play very different roles in operant behavior and the immune system. However, in all three systems, iteration is central. All three selection processes are also incredibly wasteful and inefficient. They can generate complexity and novelty primarily because they are so wasteful and inefficient. Key Words: evolution; immunology; interaction; operant behavior; operant learning; replication; selection; variation. (shrink)

Criticized as a nostalgic anachronism by those who oppose her version of political theory and lauded as symbol of direct democratic participation by those who favor it, the Athenian polis features prominently in Hannah Arendt's account of politics. This essay traces the origin and development of Arendt's conception of the polis as a space of appearance from the early 1950s onward. It makes particular use of the Denktagebuch, Arendt's intellectual diary, in order to shed new light on the historicity of (...) one of her central concepts. The article contends that both critics and partisans of Arendt's use of the polis have made the same mistake: they have presumed that the polis represents a space of face-to-face immediacy. In fact, Arendt compared the polis to a series of analogues, many of which are not centered on direct exchanges between political actors and spectators. As a result, Arendt's early work on the polis turns out to anticipate many of the concerns of her later work on judgment, and her theory of the polis becomes a theory of topics. (shrink)

After briefly narrating the evolution of Western ethical reflections on suicide and euthanasia, I argue that because people have a prima facie right not to be killed, it is usually unethical to kill anyone who poses no imminent lethal threat to others or who has not committed a capital crime. But I’m also persuaded that some instances of mercy killing in war are not only morally justifiable, they can be more ethical than allowing someone to die in agony and distress (...) from their wounds. Thus I am uncomfortable with the current strict prohibition on battlefield euthanasia in the Geneva Conventions, which I think unfairly punishes some morally justified acts. But after considering the potential consequences of legalizing battlefield euthanasia, I conclude nonetheless that it is best to leave the prohibition intact. (shrink)

The author proposes a system of identification, positional, and phyletic numbers for taxa that makes possible a significant relationship between numerical classification and phylogeny.

: Testing the claims that scientists make is extremely difficult. Testing the claims that philosophers of science make about science is even more difficult, difficult but not impossible. I discuss three efforts at testing the sorts of claims that philosophers of science make about science: the influence of scientists' age on the alacrity with which they accept new views, the effect of birth order on the sorts of contributions that scientists make, and the role of novel predictions in the acceptance (...) of new scientific views. Without attempting to test philosophical claims, it is difficult to know what they mean. (shrink)

It seems that Whitehead's original problem, as evidenced in his earlier works, was epistemological and metaphysical dualism. His method of extensive abstraction is an attempt to bring the factual world and the abstract world of thought together. So far as his books on nature are concerned, then, Whitehead denied the ultimate reality of a static world and accepted the reality of dynamic relations analogous to the relations found in a biological organism.

Henry Thoreau boasted that he was widely travelled in Concord, Massachusetts. He was born there on 12 July 1817, and he died there on 6 May 1862, of tuberculosis, at the age of forty-four years. In 1837 he graduated from Harvard College, and in 1838 he joined Ralph Waldo Emerson, Margaret Fuller, and others in the informal group that became known as the New England Transcendentalists. The author of four books, many essays and poems, and a voluminous journal, he is (...) best known for the book Walden and the essay ‘Civil Disobedience’, and for the circumstances attending these two milestones in American thought and literature. (shrink)

"Legend is overdue for replacement, and an adequate replacement must attend to the process of science as carefully as Hull has done. I share his vision of a serious account of the social and intellectual dynamics of science that will avoid both the rosy blur of Legend and the facile charms of relativism.... Because of [Hull's] deep concern with the ways in which research is actually done, Science as a Process begins an important project in the study of science. It (...) is one of a distinguished series of books, which Hull himself edits."—Philip Kitcher, Nature "In Science as a Process, [David Hull] argues that the tension between cooperation and competition is exactly what makes science so successful.... Hull takes an unusual approach to his subject. He applies the rules of evolution in nature to the evolution of science, arguing that the same kinds of forces responsible for shaping the rise and demise of species also act on the development of scientific ideas."—Natalie Angier, New York Times Book Review "By far the most professional and thorough case in favour of an evolutionary philosophy of science ever to have been made. It contains excellent short histories of evolutionary biology and of systematics (the science of classifying living things); an important and original account of modern systematic controversy; a counter-attack against the philosophical critics of evolutionary philosophy; social-psychological evidence, collected by Hull himself, to show that science does have the character demanded by his philosophy; and a philosophical analysis of evolution which is general enough to apply to both biological and historical change."—Mark Ridley, Times Literary Supplement "Hull is primarily interested in how social interactions within the scientific community can help or hinder the process by which new theories and techniques get accepted.... The claim that science is a process for selecting out the best new ideas is not a new one, but Hull tells us exactly how scientists go about it, and he is prepared to accept that at least to some extent, the social activities of the scientists promoting a new idea can affect its chances of being accepted."—Peter J. Bowler, Archives of Natural History "I have been doing philosophy of science now for twenty-five years, and whilst I would never have claimed that I knew everything, I felt that I had a really good handle on the nature of science, Again and again, Hull was able to show me just how incomplete my understanding was.... Moreover, [Science as a Process] is one of the most compulsively readable books that I have ever encountered."—Michael Ruse, Biology and Philosophy. (shrink)